What is the typical first line of chemotherapy treatment for advanced endometrial cancer?
What is the typical first line of chemotherapy treatment for advanced endometrial cancer?
Answer by Don Dizon, MD (Oncology - Hematology/Oncology specialist)
A: The typical treatment is a combination treatment, usually using platinum based chemotherapy. Two regimens are used commonly: carboplatin and paclitaxel or the three drug combination of cisplatin, doxorubicin, and paclitaxel. Carboplatin is far more tolerable than cisplatin, so I tend to use carboplatin plus paclitaxel. The preliminary results from a Gynecologic Oncology Group trial presented this year at our Society for Gynecologic Oncologists Annual Meeting suggested they were equivalent.
His webpage:http://research.brown.edu/myresearch/Don_S_Dizon